product description:
Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.
Disclosure of Affiliate Relationships
• buynorthbest.com participates in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. Since 2022, our goal has been to provide value to our visitors by carefully curating and recommending bestselling and interesting products. While we may earn a small commission from qualifying purchases made through affiliate links, this comes at no additional cost to you. Your support helps us continue offering high-quality content and product recommendations.
• We are assuming you have read our
terms and conditions and agreed with them.
Famous Brands 2025:
Was this product Helpful?
